I don’t think it’s a good idea to hold the Virtual Boy by the stand. I prefer to hold it by grabbing the head unit on the right side with the right hand and the middle of the stand by the left three fingers on the left hand.
Well, actually, my VB is always less than 1 meter away from me when I’m at my computer, so I just keep the controller attached because the cable’s long enough, and it’s not too much trouble either to disconnect it. But yeah, while playing, holding it by the stand is pretty much the only solution. But you could just take it off the stand.